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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VPS39
All Species:
36.97
Human Site:
T269
Identified Species:
67.78
UniProt:
Q96JC1
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96JC1
NP_056104.2
886
101809
T269
P
R
Y
V
E
I
R
T
F
E
P
R
L
L
V
Chimpanzee
Pan troglodytes
XP_510331
886
101752
T269
P
R
Y
V
E
I
R
T
F
E
P
R
L
L
V
Rhesus Macaque
Macaca mulatta
XP_001102792
886
101693
T269
P
R
Y
V
E
I
R
T
F
E
P
R
L
L
V
Dog
Lupus familis
XP_849407
886
101720
T269
P
R
Y
V
E
I
R
T
F
E
P
R
L
L
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8R5L3
886
101674
T269
P
R
Y
V
E
I
R
T
L
E
P
R
L
L
V
Rat
Rattus norvegicus
XP_001075756
886
101629
T269
P
R
Y
V
E
I
R
T
L
E
P
R
L
L
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518189
1309
145152
L692
E
H
Q
L
C
T
R
L
Q
H
P
R
S
T
Q
Chicken
Gallus gallus
NP_001026365
875
100503
T258
P
R
Y
V
E
I
R
T
F
E
P
R
L
L
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A4IG72
863
97029
S272
E
G
F
V
T
V
H
S
M
L
D
Q
Q
L
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650702
876
100146
W257
S
S
L
T
P
L
L
W
S
S
P
L
L
D
L
Honey Bee
Apis mellifera
XP_392710
866
100055
T263
H
D
R
L
E
V
Y
T
T
E
G
C
L
H
I
Nematode Worm
Caenorhab. elegans
NP_001041163
923
104932
S281
K
G
R
V
E
V
R
S
I
F
D
G
Q
L
V
Sea Urchin
Strong. purpuratus
XP_798217
824
94304
T263
P
K
Y
V
E
V
R
T
V
D
P
R
L
L
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99.3
98
N.A.
97.4
96.8
N.A.
59.2
92.7
N.A.
26.4
N.A.
35.4
42.4
31.7
51.5
Protein Similarity:
100
99.8
99.7
99.3
N.A.
98.9
98.5
N.A.
62.8
96.1
N.A.
46.8
N.A.
55.6
62
52.5
68.4
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
20
100
N.A.
13.3
N.A.
13.3
26.6
33.3
73.3
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
26.6
100
N.A.
40
N.A.
26.6
46.6
46.6
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
8
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
0
8
0
0
0
0
0
0
0
8
16
0
0
8
0
% D
% Glu:
16
0
0
0
77
0
0
0
0
62
0
0
0
0
0
% E
% Phe:
0
0
8
0
0
0
0
0
39
8
0
0
0
0
0
% F
% Gly:
0
16
0
0
0
0
0
0
0
0
8
8
0
0
0
% G
% His:
8
8
0
0
0
0
8
0
0
8
0
0
0
8
0
% H
% Ile:
0
0
0
0
0
54
0
0
8
0
0
0
0
0
8
% I
% Lys:
8
8
0
0
0
0
0
0
0
0
0
0
0
0
8
% K
% Leu:
0
0
8
16
0
8
8
8
16
8
0
8
77
77
8
% L
% Met:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
62
0
0
0
8
0
0
0
0
0
77
0
0
0
0
% P
% Gln:
0
0
8
0
0
0
0
0
8
0
0
8
16
0
8
% Q
% Arg:
0
54
16
0
0
0
77
0
0
0
0
70
0
0
0
% R
% Ser:
8
8
0
0
0
0
0
16
8
8
0
0
8
0
0
% S
% Thr:
0
0
0
8
8
8
0
70
8
0
0
0
0
8
0
% T
% Val:
0
0
0
77
0
31
0
0
8
0
0
0
0
0
70
% V
% Trp:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% W
% Tyr:
0
0
62
0
0
0
8
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _